Our experts have hand-selected the top recommendations for guest bedrooms based on quality, budget and durability. When choosing a mattress for a guest bedroom, take into account who’s going to be visiting you the most. If it’s aging parents, opt for a firmer mattress that will allow them to get in and out of bed easily, while also offering optimal spinal support. If you’re going to have little nieces, nephews, or grandchildren visiting for a few days, a softer feeling mattress would be a practical option. If you have a rotating door of different preferences and ages, choosing a medium firmness, like our Amsterdam Mattress, is ideal to keep your guests happy.